Which of the following can lead to decreased liver function and bile stasis?

Caroli's Disease is indeed associated with decreased liver function and bile stasis. This condition is characterized by the presence of cystic dilatation of the intrahepatic bile ducts. These dilated ducts can obstruct bile flow, leading to stasis and potential or actual liver dysfunction over time.

In Caroli's Disease, the cystic formations primarily affect the liver's ability to transport bile effectively. This obstruction contributes to cholestasis, which is a condition where bile cannot flow from the liver to the duodenum, and can lead to complications such as infections and further hepatic impairment. Because bile stasis can result in an environment conducive to the growth of bacteria, there is an increased risk of cholangitis as a complication, further impacting liver function.

In contrast, while options like cholangitis and acute cholecystitis involve inflammation of biliary structures that can cause symptoms and complications related to liver function, they are more directly acute conditions affecting the biliary tract and not primarily characterized by structural changes of the bile ducts as seen in Caroli's Disease. Mirizzi Syndrome, on the other hand, is a specific complication of gallstones causing bile duct obstruction and can lead to similar issues, but again, it doesn't entail the