Which condition is not typically associated with adrenal cortex disorders?

Pheochromocytoma is indeed not typically associated with adrenal cortex disorders. This condition is primarily linked to the adrenal medulla, which is the innermost part of the adrenal glands. Pheochromocytoma is a tumor that produces excess catecholamines (such as adrenaline), leading to symptoms like hypertension, palpitations, and perspiration.

On the other hand, Addison's disease, Cushing's syndrome, and Conn's syndrome are all disorders that directly involve the adrenal cortex. Addison's disease results from the inadequate production of hormones such as cortisol and aldosterone due to adrenal insufficiency. Cushing's syndrome is characterized by an overproduction of cortisol, often due to a tumor or other pathology affecting the adrenal cortex. Conn's syndrome, also known as primary hyperaldosteronism, involves excessive production of aldosterone, which can lead to hypertension and electrolyte imbalances.

Thus, the distinction lies in the origin and nature of the disorders; Pheochromocytoma arises from the adrenal medulla, while the others are rooted in the adrenal cortex's functioning.