Which condition is identified by excessive secretion of glucocorticoids?

Cushing's Syndrome is characterized by excessive secretion of glucocorticoids, particularly cortisol. This condition typically arises due to abnormalities in the adrenal glands, such as adrenal tumors or pituitary adenomas that lead to increased production of adrenocorticotropic hormone (ACTH). Elevated levels of cortisol can result in various physical changes, including weight gain, facial rounding, increased fat around the neck, and a variety of metabolic issues.

In addition to its systemic effects, Cushing's Syndrome is often associated with specific symptoms like purple striae on the skin, easy bruising, and hypertension. The diagnosis usually involves a combination of clinical evaluation and biochemical testing, such as 24-hour urinary free cortisol levels or suppression tests.

The other conditions listed do not lead to excessive glucocorticoid production. Addison's Disease is characterized by insufficient production of adrenal hormones, including glucocorticoids. Adrenogenital Syndrome results from excess androgens, leading to virilization but not specifically elevated glucocorticoids. Conn's Syndrome is associated with excess aldosterone secretion, leading to issues related to sodium and water retention, rather than glucocorticoid levels.