What type of cell in the pancreas is responsible for secreting glucagon?

The alpha cells in the pancreas are responsible for secreting glucagon, a hormone that plays a critical role in glucose metabolism. When blood glucose levels drop, glucagon is released by these cells to signal the liver to convert stored glycogen into glucose, which is then released into the bloodstream. This action helps to increase blood glucose levels, effectively counterbalancing the effects of insulin, which lowers glucose levels. Understanding the functions of these different types of cells in the pancreas is essential for grasping how endocrine regulation of metabolism operates, emphasizing the alpha cells' pivotal role in maintaining glucose homeostasis.