What tumor is associated with excessive secretion of epinephrine and norepinephrine?

The tumor associated with excessive secretion of epinephrine and norepinephrine is pheochromocytoma. This type of tumor typically arises from chromaffin cells in the adrenal medulla and is characterized by its ability to produce and secrete catecholamines, which include epinephrine and norepinephrine. The overproduction of these hormones leads to symptoms such as hypertension, palpitations, headache, and sweating.

Pheochromocytomas can be sporadic or part of hereditary syndromes, such as multiple endocrine neoplasia (MEN) types 2A and 2B. Diagnosing this condition often involves measuring catecholamine levels in plasma and urine, and imaging studies may be utilized to locate the tumor.

In contrast, other tumors listed, such as neuroblastoma, typically affect children and may secrete catecholamines, but they are not primarily characterized by excessive secretion of epinephrine and norepinephrine in the same way that pheochromocytoma is. Medullary thyroid carcinoma is associated with calcitonin secretion, and adrenal cortical carcinoma relates more to cortisol and other steroid hormone production rather than catecholamines.