What term refers to the kidneys' inability to filter metabolites from the blood, resulting in decreased function?

The term that refers to the kidneys' inability to filter metabolites from the blood, resulting in decreased function, is renal failure. Renal failure indicates a significant decline in the kidneys' ability to perform their essential functions, including the filtration of waste products and regulation of electrolyte balance. This condition can lead to the accumulation of toxins in the bloodstream, which can be detrimental to overall health.

Renal failure can be classified into two main types: acute and chronic. Acute renal failure occurs suddenly and may be reversible, while chronic renal failure develops gradually and can lead to end-stage kidney disease if not managed properly. The focus on the kidneys' ineffective filtering capacity makes renal failure the most appropriate term in this context.